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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB2
All Species:
27.58
Human Site:
S54
Identified Species:
43.33
UniProt:
Q9UBS0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBS0
NP_003943.2
482
53483
S54
E
V
E
L
T
E
T
S
V
N
V
G
P
E
R
Chimpanzee
Pan troglodytes
XP_001172909
482
53404
S54
E
V
E
L
T
E
T
S
V
N
L
G
P
E
R
Rhesus Macaque
Macaca mulatta
XP_001117937
512
56562
S81
E
V
E
L
T
E
T
S
V
N
L
C
P
E
R
Dog
Lupus familis
XP_851971
482
53401
S52
E
V
E
L
T
E
T
S
V
N
L
G
P
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z1M4
485
53520
S54
E
V
E
L
T
E
S
S
V
N
L
G
P
E
R
Rat
Rattus norvegicus
P67999
525
59113
S78
K
F
E
I
S
E
T
S
V
N
R
G
P
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
P45
R
G
P
E
K
I
R
P
E
C
F
E
L
L
R
Chicken
Gallus gallus
P18652
752
84421
E61
K
G
E
G
V
V
K
E
I
N
I
T
H
H
V
Frog
Xenopus laevis
P10665
733
82620
D58
K
E
G
S
E
K
A
D
Q
S
D
F
V
L
L
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
V55
E
I
P
I
T
H
H
V
K
E
G
C
E
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S182
E
I
D
E
S
S
S
S
L
S
K
A
K
S
N
Honey Bee
Apis mellifera
XP_395876
456
51514
N56
T
V
P
I
S
E
Q
N
V
N
R
G
R
E
R
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
E86
T
D
S
S
S
E
T
E
I
D
I
G
D
V
R
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
T59
E
V
S
L
S
E
E
T
V
N
P
G
T
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
M48
F
S
D
V
F
G
P
M
P
E
A
N
S
E
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
91.8
95
N.A.
92.9
65.7
N.A.
70.9
30
30.5
30.2
N.A.
21.1
56.8
29.9
60.9
Protein Similarity:
100
99.7
92.5
96.6
N.A.
95
76
N.A.
80.9
42.8
42.5
43.2
N.A.
28.3
70.7
43.1
74.5
P-Site Identity:
100
93.3
86.6
93.3
N.A.
86.6
60
N.A.
6.6
13.3
0
13.3
N.A.
13.3
46.6
26.6
53.3
P-Site Similarity:
100
100
93.3
100
N.A.
100
86.6
N.A.
6.6
33.3
20
33.3
N.A.
53.3
66.6
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
39.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
7
0
0
0
7
7
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
14
0
0
0
% C
% Asp:
0
7
14
0
0
0
0
7
0
7
7
0
7
0
0
% D
% Glu:
54
7
47
14
7
60
7
14
7
14
0
7
7
60
7
% E
% Phe:
7
7
0
0
7
0
0
0
0
0
7
7
0
0
0
% F
% Gly:
0
14
7
7
0
7
0
0
0
0
7
54
0
0
0
% G
% His:
0
0
0
0
0
7
7
0
0
0
0
0
7
7
0
% H
% Ile:
0
14
0
20
0
7
0
0
14
0
14
0
0
0
0
% I
% Lys:
20
0
0
0
7
7
7
0
7
0
7
0
7
7
14
% K
% Leu:
0
0
0
40
0
0
0
0
7
0
27
0
7
14
7
% L
% Met:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
7
0
60
0
7
0
0
7
% N
% Pro:
0
0
20
0
0
0
7
7
7
0
7
0
40
0
0
% P
% Gln:
0
0
0
0
0
0
7
0
7
0
0
0
0
0
0
% Q
% Arg:
7
0
0
0
0
0
7
0
0
0
14
0
7
0
54
% R
% Ser:
0
7
14
14
34
7
14
47
0
14
0
0
7
7
0
% S
% Thr:
14
0
0
0
40
0
40
7
0
0
0
7
7
0
0
% T
% Val:
0
47
0
7
7
7
0
7
54
0
7
0
7
7
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _